Academic Degrees
2011: master's degree from Wuhan University, China
2016: Ph.D. degree from the University of Missouri, the United States
Professional Experience
2019-present: Associate Professor; the School of Physics, Huazhong University of Science and Technology，ChinaProfessional Experience
2016-2019: Postdoc; the Department of Molecular Biophysics and Biochemistry, Yale University, United States
Selected Publications
Y. Si, C. Yan* A reproducibility analysis-based statistical framework for evolutionary coupling detection, Briefings in Bioinformatics (Accepted),https://doi.org/10.1101/2021.02.01.429092
Y. Si, C. Yan*, Improved protein contact prediction using dimensional hybrid residual networks and singularity enhanced loss function, Briefings in Bioinformatics 2021, 22, bbab341
B. Wang#, C. Yan#et al. Building a hybrid physical-statistical classifier for predicting the effect of variants related to protein-drug interactions. Structure 2019, 27, 1469-1481.
C. Yan, X. Zou. Modeling protein flexibility in molecular docking, Comprehensive in Medicinal Chemistry III 2017, 3, 318-328.
C. Yan, X. Xu, X. Zou. Fully blind docking at the atomic level for protein-peptide complex structure prediction, Structure 2016, 24, 1842-1853.
C. Yan,et al.Iterative knowledge-based scoring functions derived from rigid flexible decoy structures: evaluation with the 2013 and 2014 CSAR benchmarks, Journal of Chemical Information and Modeling 2016, 56, 1012-1021.
C. Yan, X. Zou. Predicting peptide binding sites on protein surfaces by clustering chemical interactions, Journal of Computational Chemistry 2015, 36, 49-61 (Featured by the inside cover).
Courses Taught：
Biological Data Analysis and Modeling, Biological Physics, College Experimental Physics
Project：
National Natural Science Foundation of China：32101001, predicting residue-residue contacts between interacting proteins through integrative searching of interolog sequences and deep learning from January, 2022 to December, 2024
